Etrebelle PCL – HA + PCL Hybrid Filler

Etrebelle PCL logo

Etrebelle is a hybrid filler that has adopted both benefits of the immediate filling effect of HA and stimulating collagen production of PCL under the skin. Based on the idea of delivering PCL (Polycaprolactone) microparticles by HA (Sodium Hyaluronate), not only physical supports under the skin, Etrebelle improves the fundamental deficiency of volume loss by collagen restoration.

Etrebelle PCL vial filled with HA (sodium hyaluronate) for intensive moisturization and PCL (polycaprolactone) microparticles for collagen production
Etrebelle right after injection: HA gel physically supports the area while holding the microparticles in place

After Injection

Physical Support

Right after injection, Etrebelle takes a position and instantly supports the wrinkled area with its HA material. Meanwhile, included PCL microparticles help HA not to migrate from the target area by giving extra cohesiveness.

Etrebelle after 1 month: HA begins to degrade as the microparticles stimulate new collagen fibers

After 1 Month

Restoration

After 1 month, while HA starts to be degraded, PCL microparticles promote collagen production and lead to even more elastic skin conditions. The mixture ratio of Etrebelle is remarked from this turning point of each materials' interaction under the skin.

Etrebelle after 6 months: new collagen fibers surround the remaining microparticles and maintain volume

After 6 Months

Maintenance

After 8 month, the outcome of Etrebelle can be shown which has been gradually biodegraded and restore the skin volume from its physical support to newly synthesized collagen fibers maintain the natural result over time.

Etrebelle after 24 months: microparticles fully eliminated, leaving newly formed collagen fibers

After 24 Months

Elimination

After 24 months, PCL microparticles slowly degrade into carbon dioxide and water through non-enzymatic hydrolysis in the body. Eventually, the microparticles are completely eliminated, leaving no leftovers but restoring skin volume with enriched collagen fibers.

Etrebelle PCL 200 vial: PCL + HA, 200 mg per vial

Deep furrows correction

Massive volumization

Etrebelle PCL 200

(PCL: 100mg + HA: 100mg)

PCL particle: 60-80μm

HA particle: 1,400kDa

Mixture: Sterile distilled water 9cc + Lidocaine 1cc

(dilution time: over 30min)

Cannula size: 25-27G

Etrebelle PCL 200 composition: HA 1,400 kDa 100 mg and PCL 100 mg